The ninth track, 'Up' samples Tevin Campbell's 'Could It Be'. The tenth track, 'Never Been' samples 'Schala's Theme' from it 's soundtrack to the video game Chrono Trigger, from which is a same name as its other soundtrack, composed by Yasunori Mitsuda. The eighth track, 'The Kid Frankie' samples Loose Ends' ' Hangin' on a String', in which Khalifa had previously stated that the song was inspired by the character named Frankie from the film The Business (2005), who listens to Loose Ends, while traveling around Spain and other countries. The subject matter mainly consisted of partying, pretty women, sex, and marijuana. The mixtape's cover artwork was an homage to David Ruffin's album Gentleman Ruffin (1980).

In an interview with MTV's Mixtape Daily, Wiz Khalifa stated that Kush and Orange Juice would be the title for this release, because 'it's perfect for wake-and-bake'. The hashtag #kushandorangejuice became the number-six trending topic on the microblogging service after its release and remained on the top trending items on Twitter for three days. On the same day, a link to the mixtape was posted for download on Wiz’s Twitter.

Kush & Orange Juice gained notoriety after its official release by making it the number-one trending topic on both Google and Twitter. It was released on April 14, 2010, by Taylor Gang Records and Rostrum Records. Kush & Orange Juice (stylzed as Kush and OJ) is the eighth mixtape by American rapper Wiz Khalifa.

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